Mechanism study on the effect of androgen antagonism in prostate cancer

CONCLUSION: Under the action of 4-HNE, the expression of AR-MAPK pathway related proteins increase. 4-HNE may promote the progression of prostate cancer through the AR-MAPK pathway, and 4-HNE is expected to become a new therapeutic target for CRPC.PMID:38602755

Source: Cancer Control - April 11, 2024 Category: Cancer & Oncology Authors: Xu Song Qiang Song Rong Wang Qing-Jun Zuo Zhi-Yuan Zhang Source Type: research