Single-cell RNA sequencing reveals cell-cell communication and potential biomarker in sepsis and septic shock patients

CONCLUSIONS: In summary, our work demonstrates changes in cell-cell communication of healthy controls, sepsis and septic shock, confirming that the molecules CAP-1 and IL16 on monocytes may serve as potential diagnostic markers for sepsis and septic shock, respectively. These findings provide new insights for early diagnosis and stratified treatment of the disease.PMID:38593502 | DOI:10.1016/j.intimp.2024.111938

Source: International Immunopharmacology - April 9, 2024 Category: Allergy & Immunology Authors: Guilin Li Zhaoxu Yang Chen Yang Yaochen Xie Shuchen Gong Shuying Lv Boneng Xiao Jiajia Wang Qinjie Weng Jincheng Wang Feng Yu Source Type: research