Characterization of Chronic Ocular Pain Using the Neurologic Pain Signature

Chronic ocular pain is a disabling condition defined by ocular spontaneous pain and allodynia. To determine whether brain network dynamics related to pain are different in patients with chronic pain vs. those without, we analyzed the functional connectivity between the constituent brain regions that comprise the Neurologic Pain Signature (NPS). Subjects were recruited from the Miami Veterans Affairs Medical Center and split into two groups: those with chronic ocular pain (n=60, average ocular pain ≥1/10 over 1 week recall) and those without ocular pain (n=20).
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research