ACD856, a novel positive allosteric modulator of Trk receptors, single ascending doses in healthy subjects: Safety and pharmacokinetics

ConclusionThe prediction proved accurate demonstrating the value of conducting a microdose study prior to ascending dose studies.Trial registrationNCT05783830 March 24, 2023 (microdose study, retrospectively registered) and NCT05077631 October 14, 2021 (single ascending dose study).
Source: European Journal of Clinical Pharmacology - Category: Drugs & Pharmacology Source Type: research