Effectiveness of nirmatrelvir-ritonavir versus azvudine for adult inpatients with severe or critical COVID-19

CONCLUSION: Paxlovid and azvudine had similar effectiveness on in-hospital all-cause mortality and hospital length of stay. Compared with the azvudine group, after 7 days of therapy, the degree of decline in SOFA score was significantly higher in the Paxlovid group. These findings need to be verified in larger prospective studies or randomised controlled trials.PMID:38599779 | DOI:10.1136/bmjresp-2023-001944

Source: Respiratory Care - April 10, 2024 Category: Respiratory Medicine Authors: Huan Zhang Tan Xiaojiao Junjun Chen Zheng Zhang Chenxi Wang Haiqing Shi Yao Li Jianbo Li Yan Kang Xiaodong Jin Xuelian Liao Source Type: research