Pre-Transplant T Lymphocyte Mycophenolic Acid Resistance is Associated with Aberrant Cytokine Production and Acute Rejection Among Lung Transplant Recipients

Purpose: Mycophenolic acid (MPA), the anti-proliferative immunosuppression agent of choice for lung transplant recipients, demonstrates extensive response variability. We assessed pre-transplant MPA sensitivity influence on T lymphocyte function and post-transplant outcomes in lung transplant recipients.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research