NKG2D - A Potential Target for Alloreactive CD8 T Cells

Purpose: Long term survival after lung transplantation is greatly limited by the high incidence of chronic lung allograft dysfunction (CLAD), however mechanisms are incompletely characterized and effective therapy is limited. NKG2D is a cell surface protein associated with lymphocyte cytoxicity that may be involved in CLAD pathogenesis.

Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: K. Moghbeli, , A. Craig, J. Sembrat, M. Bueno, O. Eickelberg, M. Snyder Source Type: research