Orphan GPCR GPRC5C Facilitates Angiotensin II-Induced Smooth Muscle Contraction

CONCLUSIONS: Our data show that GPRC5C regulates Ang II-dependent vascular contraction by facilitating AT1 receptor-ligand binding and signaling.PMID:38597112 | DOI:10.1161/CIRCRESAHA.123.323752

Source: Circulation Research - April 10, 2024 Category: Cardiology Authors: Tianpeng Wang Jingchen Shao Shamit Kumar Mohammad Wessam Alnouri Jorge Carvalho Stefan G ünther Cornelius Krasel Kate T Murphy Moritz B ünemann Stefan Offermanns Nina Wettschureck Source Type: research