Phenotypes of MASLD-associated hepatocellular carcinoma
Hepatocellular carcinoma (HCC) typically develops as consequence of liver cirrhosis, but HCC epidemiology has evolved drastically in recent years. Metabolic dysfunction-associated steatotic liver disease (MASLD), including metabolic dysfunction-associated steatohepatitis (MASH), has emerged as the most common chronic liver disease worldwide and a leading cause of HCC. A substantial proportion of MASLD-associated HCC (MASLD-HCC) can also develop in patients without cirrhosis. The specific pathways that trigger carcinogenesis in this context are not completely elucidated, and recommendations for HCC surveillance in MASLD patients are challenging.
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Jes ús Rivera-Esteban, Sergio Muñoz-Martínez, Mónica Higuera, Elena Sena, María Bermúdez-Ramos, Juan Bañares, María Martínez-Gomez, M Serra Cusidó, Alba Jiménez-Masip, Sven M. Francque, Frank Tacke, Beatriz Minguez, Juan M. Pericàs. Tags: Narrative Reviews Source Type: research
More News: Cancer & Oncology | Carcinoma | Cirrhosis | Epidemiology | Gastroenterology | Hepatocellular Carcinoma | Liver | Liver Cancer | Liver Disease | Urology & Nephrology