Targeting BRD4 with PROTAC degrader ameliorates LPS-induced acute lung injury by inhibiting M1 alveolar macrophage polarization

CONCLUSION: Our study suggested that targeting BRD4 using ARV-825 is a potential therapeutic approach for ALI.PMID:38581996 | DOI:10.1016/j.intimp.2024.111991

Source: International Immunopharmacology - April 6, 2024 Category: Allergy & Immunology Authors: Difei Li Yao Deng Guanxi Wen Lingwei Wang Xing Shi Shanze Chen Rongchang Chen Source Type: research