Determination of Tumor Marker Screening for Lung Cancer Using ROC Curves

CONCLUSION: The five tumor markers-CEA, CA125, CY211, NSE, GRP-show promising results in screening healthy individuals and patients with lung cancer. However, only CEA, NSE, and GRP effectively differentiate patients with benign lung lesions from those with lung cancer. A single tumor marker has limited utility in detecting and screening for lung cancer and should be combined with other tumor markers. CEA + CA125 emerges as a superior tumor marker for distinguishing healthy individuals from those with lung cancer, whereas the CEA + NSE combination is more effective in identifying tumor markers in patients with benign lung lesions and lung cancer.PMID:38549716 | PMC:PMC10978075 | DOI:10.1155/2024/4782618
Source: Disease Markers - Category: Laboratory Medicine Authors: Source Type: research