Identification novel mutations and phenotypic spectrum expanding in PATL2 in infertile women with IVF/ICSI failure

ConclusionsThese results expand the spectrum ofPATL2 variants and provide an important reference for genetic counseling for female infertility, and they increase our understanding of the mechanisms of oocyte maturation arrest caused by PATL2 deficiency.

Source: Journal of Assisted Reproduction and Genetics - March 27, 2024 Category: Reproduction Medicine Source Type: research