Predicting ischemic stroke patients ’ prognosis changes using machine learning in a nationwide stroke registry

This study aimed to overcome these gaps by utilizing a large national stroke registry database to assess various prediction models that estimate how patients ’ prognosis changes over time with associated clinical factors. To properly evaluate the best predictive approaches currently available and avoid prejudice, this study employed three different prognosis prediction models including a statistical logistic regression model, commonly used clinical-bas ed scores, and a latest high-performance ML-based XGBoost model. The study revealed that the XGBoost model outperformed other two traditional models, achieving an AUROC of 0.929 in predicting the prognosis changes of stroke patients followed for 3 months. In addition, the XGBoost model maintained r emarkably high precision even when using only selected 20 most relevant clinical features compared to full clinical datasets used in the study. These selected features closely correlated with significant changes in clinical outcomes for stroke patients and showed to be effective for predicting progn osis changes after discharge, allowing physicians to make optimal decisions regarding their patients’ recovery.Graphical Abstract
Source: Medical and Biological Engineering and Computing - Category: Biomedical Engineering Source Type: research