Omentin-1 ameliorates pulmonary arterial hypertension by inhibiting endoplasmic reticulum stress through AMPK α signaling

CONCLUSIONS: Our results reveal a protective effect of omentin-1 in PAH via inhibiting ER stress through AMPKα signaling and provide an agent with translational potential for the treatment of PAH.PMID:38527024 | DOI:10.1080/10641963.2024.2332695

Source: Clinical and Experimental Hypertension - March 25, 2024 Category: Cardiology Authors: Xinyu Deng Hao Luo Jing He Wang Deng Daoxin Wang Source Type: research