Tetramethylpyrazine Nitrone Promotes the Clearance of Alpha-Synuclein via Nrf2-Mediated Ubiquitin –Proteasome System Activation

In conclusion, TBN promotes the clearance of α-syn via Nrf2-mediated UPS activation , and it may serve as a potentially disease-modifying therapeutic agent for PD.

Source: NeuroMolecular Medicine - April 3, 2024 Category: Neurology Source Type: research