Viruses, Vol. 16, Pages 557: Sequencing and Analysis of Lumpy Skin Disease Virus Whole Genomes Reveals a New Viral Subgroup in West and Central Africa

Viruses, Vol. 16, Pages 557: Sequencing and Analysis of Lumpy Skin Disease Virus Whole Genomes Reveals a New Viral Subgroup in West and Central Africa Viruses doi: 10.3390/v16040557 Authors: Ismar R. Haga Barbara B. Shih Gessica Tore Noemi Polo Paolo Ribeca Delgerzul Gombo-Ochir Gansukh Shura Tsagaan Tserenchimed Bazarragchaa Enkhbold Dulam Purevtseren Gerelmaa Ulziibat Batchuluun Damdinjav Lama Yimer Fufa D. Bari Daniel Gizaw Adeyinka Jeremy Adedeji Rebecca Bitiyong Atai Jolly Amoche Adole Banenat Bajehson Dogonyaro Pradeep Lakpriya Kumarawadu Carrie Batten Amanda Corla Graham L. Freimanis Chandana Tennakoon Andy Law Samantha Lycett Tim Downing Philippa M. Beard Lumpy skin disease virus (LSDV) is a member of the capripoxvirus (CPPV) genus of the Poxviridae family. LSDV is a rapidly emerging, high-consequence pathogen of cattle, recently spreading from Africa and the Middle East into Europe and Asia. We have sequenced the whole genome of historical LSDV isolates from the Pirbright Institute virus archive, and field isolates from recent disease outbreaks in Sri Lanka, Mongolia, Nigeria and Ethiopia. These genome sequences were compared to published genomes and classified into different subgroups. Two subgroups contained vaccine or vaccine-like samples (“Neethling-like” clade 1.1 and “Kenya-like” subgroup, clade 1.2.2). One subgroup was associated with outbreaks...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research