Early-onset dementia and risk of hip fracture and major osteoporotic fractures

DISCUSSION: EOD patients have a higher risk of osteoporotic fractures than cognitively healthy individuals. The use of cholinesterase inhibitors may reduce the risk of hip fracture among EOD patients.HIGHLIGHTS: It is unknown whether early-onset dementia (EOD) increases the risk of fractures. We identified 13,614 individuals with EOD using a nationwide administrative database. Patients with EOD have a higher risk of hip, vertebral, and major osteoporotic fractures. The use of cholinesterase inhibitors may reduce hip fracture among patients with EOD.PMID:38561022 | DOI:10.1002/alz.13815

Source: The Journal of Alzheimers Association - April 1, 2024 Category: Psychiatry Authors: Shoya Matsumoto Tatsuya Hosoi Mitsutaka Yakabe Kenji Fujimori Junko Tamaki Shinichi Nakatoh Shigeyuki Ishii Nobukazu Okimoto Masahiro Akishita Masayuki Iki Sumito Ogawa Source Type: research