Effects of SNPs on TNF- α and IL-10 cytokine expression in TB and HIV patients in the Capricorn district, Limpopo Province, South Africa

Conclusion: Our data showed that the gene variants were not associated with circulating plasma levels of TNF- α and IL-10 in our study population. A pro-inflammatory environment was found in the TB and TB-HIV groups, which is suggesting of bacterial clearance, while an anti-inflammatory environment was found in the HIV group, which suggests the suppression ofviral replication.Keywords: Tuberculosis; Human immunodeficiency virus; interleukin-10.
Source: African Health Sciences - Category: African Health Authors: Source Type: research