Resolving neuroinflammatory and social deficits in ASD model mice: Dexmedetomidine downregulates NF- κB/IL-6 pathway via α2AR

This study provides the first evidence of the beneficial effects of dexmedetomidine on core symptoms of ASD and offers a theoretical basis and potential therapeutic approach for the clinical treatment of ASD.PMID:38552922 | DOI:10.1016/j.bbi.2024.03.040

Source: Brain, Behavior, and Immunity - March 29, 2024 Category: Neurology Authors: Zheng-Kai Liang Wei Xiong Chen Wang Li Chen Xin Zou Jing-Wen Mai Bo Dong Chongqi Guo Wen-Jun Xin De-Xing Luo Ting Xu Xia Feng Source Type: research