F1 fraction isolated from Mesobuthus eupeus scorpion venom induces macrophage polarization toward M1 phenotype and exerts anti-tumoral effects on the CT26 tumor cell line

In conclusion, our findings demonstrated the potential of Mesobuthus eupeus venom in M2-to-M1 macrophage polarization as a promising therapeutic approach against proliferation and metastasis of colon cancer cells.PMID:38554440 | DOI:10.1016/j.intimp.2024.111960

Source: International Immunopharmacology - March 30, 2024 Category: Allergy & Immunology Authors: Mahvash Sadeghi Afshin Amari Ali Asadirad Mohammad Nemati Ali Khodadadi Source Type: research