Deletion of Dictyostelium tpc2 gene forms multi-tipped structures, regulates autophagy and cell-type patterning

CONCLUSION: TPC2 is required for effective development and differentiation in Dictyostelium and supports autophagic cell death and cell-type patterning.SIGNIFICANCE: Decreased calcium due to deletion of tpc2 inhibit autophagic flux.PMID:38537110 | DOI:10.1111/boc.202300067

Source: Biology of the Cell - March 27, 2024 Category: Cytology Authors: Madhubala Rathore Ashima Thakur Shweta Saran Source Type: research