GINS2 promotes the progression of human HNSCC by altering RRM2 expression

CONCLUSION: Our study reported the role of GINS2 in HNSCC for the first time. The results demonstrated that in HNSCC cells, GINS2 promoted proliferation and inhibited apoptosis via altering RRM2 expression. Therefore, GINS2 might play a carcinogen in HNSCC, and become a specific promising therapeutic target.PMID:38517779 | DOI:10.3233/CBM-230337

Source: Cancer Biomarkers - March 22, 2024 Category: Cancer & Oncology Authors: Tianxiang Wang Luxi Qian Pingchuan Zhang Mingyu Du Jing Wu Fanyu Peng Chengyun Yao Rong Yin Li Yin Xia He Source Type: research