Single-cell multiplex chromatin and RNA interactions in ageing human brain

Nature, Published online: 27 March 2024; doi:10.1038/s41586-024-07239-wWe introduce multinucleic acid interaction mapping in single cells (MUSIC), for concurrent profiling of multiplex chromatin interactions, gene expression and RNA–chromatin associations within individual nuclei, as a tool for exploring chromatin architecture and transcription.

Source: Nature AOP - March 27, 2024 Category: Research Authors: Xingzhao Wen Zhifei Luo Wenxin Zhao Riccardo Calandrelli Tri C. Nguyen Xueyi Wan John Lalith Charles Richard Sheng Zhong Source Type: research