The different analgesic effects of alpha high-definition transcranial alternating current stimulation over the primary sensorimotor cortex and the left dorsolateral prefrontal cortex during sustained experimental pain

Pain is an unpleasant combination of sensations and emotions that is intricately controlled by neural oscillations and interconnections across different brain regions and waves [1]. Within pain-induced neural symphony, brain oscillations within the alpha frequency band (8 –13 HZ) exert regulatory control over the processing of incoming sensory information, utilizing inhibitory pathways to promote pain relief. Studies have consistently identified alpha oscillation as a promising target for potential analgesic interventions [2,3].

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 26, 2024 Category: Neurology Authors: Xingang Qi, Tianzhe Jia, Chuan Zhang, Wenjie Su, Zhiqiang Pan, Chenxi Wang, Hanfeng Yang, Jixin Liu Source Type: research