Evaluation of metagenomic and pathogen-targeted next-generation sequencing for diagnosis of meningitis and encephalitis in adults: A multicenter prospective observational cohort study in China
Next-generation sequencing (NGS) might aid in identification of causal pathogens. However, the optimal approaches applied to cerebrospinal fluid (CSF) for detection are unclear, and studies evaluating application of different NGS workflows for diagnosis of intracranial infections are limited.
Source: Journal of Infection - Category: Infectious Diseases Authors: Weibi Chen, Gang Liu, Lili Cui, Fei Tian, Jiatang Zhang, Jiahua Zhao, Ying Lv, Jianxin Du, Xinyu Huan, Yingfeng Wu, Yan Zhang Source Type: research