TNF receptor-2 signals clear-cell renal carcinoma proliferation via phosphorylated-4EBP1 and mitochondrial gene translation

In this study, phosphorylated-4EBP1 serine 65 (pSer65-4EBP1) is identified as a downstream target of this TNFR2 signalling pathway.

Source: American Journal of Pathology - March 25, 2024 Category: Pathology Authors: Rafia S. Al-Lamki, Aviva M. Tolkovsky, Mohammad Alawwami, WanHua Lu, Sarah F. Field, Jun Wang, Jordan S. Pober, John R. Bradley Tags: Regular Article Source Type: research