Neutralizing antibody responses to SARS-CoV-2 Omicron variants: Post six months following two-dose & amp; three-dose vaccination of ChAdOx1 nCoV-19 or BBV152

CONCLUSIONS: Persistence of NAb responses was comparable in individuals with two- and three-dose groups post six months of vaccination. Among the Omicron sub-variants, XBB.1 showed marked neutralization escape, thus pointing towards an eventual immune escape, which may cause more infections. Further, the correlation of study data with complete clinical profile of the participants along with observations for cell-mediated immunity may provide a clear picture for the sustained protection due to three-dose vaccination as well as hybrid immunity against the newer variants.PMID:38517215 | DOI:10.4103/ijmr.ijmr_948_23
Source: The Indian Journal of Medical Research - Category: Biomedical Science Authors: Source Type: research