Deciphering the shift from benign to active relapsing-remitting multiple sclerosis: Insights into T regulatory cell dysfunction and apoptosis regulation

CONCLUSIONS: The intricate gene regulatory networks that operate in switching-BMS are related to suppression of immune tolerance and aberrant apoptosis. These findings may lead to new therapeutic targets to prevent the escalation to active disease.PMID:38521093 | DOI:10.1016/j.nbd.2024.106475

Source: Neurobiology of Disease - March 23, 2024 Category: Neurology Authors: Anat Achiron Rina Falb Shay Menascu David Magalashvili Mathilda Mandel Polina Sonis Michael Gurevich Source Type: research