A triggered DNA nanomachine with enzyme-free for the rapid detection of telomerase activity in a one-step method

In conclusion, our study demonstrated that the triggered-DNA nanomachine fulfills the requirements for rapid detection of telomerase activity in one-step under isothermal and enzyme-free conditions with excellent specificity, and its simple and stable structure makes it ideal for complex systems. These findings indicated the application prospect of DNA nanomachines in clinical diagnostics and provided new insights into the field of DNA nanomachine-based bioanalysis.PMID:38499416 | DOI:10.1016/j.aca.2024.342420
Source: Analytica Chimica Acta - Category: Chemistry Authors: Source Type: research