An exploratory view into allelic drop-out of sequenced autosomal STRs

This study supports using common allelic drop-out factors used in fragment length analysis on sequenced STRs while including additional locus, sample, and run specific information. Results demonstrate multiple factors that can be considered when developing probability of allelic drop-out models for sequenced autosomal STRs including locus-specific analysis, total read count of a profile, and total read count sequenced on a flow cell.PMID:38505986 | DOI:10.1111/1556-4029.15504

Source: Journal of Forensic Sciences - March 20, 2024 Category: Forensic Medicine Authors: Megan M Foley Gerwald Koehler Jun Fu Robert Allen Jarrad R Wagner Source Type: research