Epigenetic MLH1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques

Naturally occurring colorectal cancers (CRC) in rhesus macaques share many features with their human counterparts and are useful models for cancer immunotherapy; but mechanistic data are lacking regarding the ...

Source: Journal of Translational Medicine - March 19, 2024 Category: Research Authors: Simon Deycmar, Brendan J. Johnson, Karina Ray, George W. Schaaf, Declan Patrick Ryan, Cassandra Cullin, Brandy L. Dozier, Betsy Ferguson, Benjamin N. Bimber, John D. Olson, David L. Caudell, Christopher T. Whitlow, Kiran Kumar Solingapuram Sai, Emily C. R Tags: Research Source Type: research