Renal toxicity of ifosfamide in children with cancer: an exploratory study integrating aldehyde dehydrogenase enzymatic activity data and a wide-array urinary metabolomics approach

Ifosfamide is a major anti-cancer drug in children with well-known renal toxicity. Understanding the mechanisms underlying this toxicity could help identify children at increased risk of toxicity.

Source: BMC Pediatrics - March 19, 2024 Category: Pediatrics Authors: Olivia Febvey-Combes, J érôme Guitton, Perrine Marec-Berard, Cécile Faure-Conter, Ellen Blanc, Sylvie Chabaud, Agnès Conjard-Duplany, Matthias Schell and Laurence Derain Dubourg Tags: Research Source Type: research