Single-Anastomosis Duodeno-ileal Bypass with Sleeve Gastrectomy as an Ultimate Option for Diabetics with Severe Obesity: A Scoping Review

This study provides a synthesis and summary of literature evidence on single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) as a treatment option for severe obesity in diabetes using a scoping review method.Recent FindingsThe review included seventeen relevant studies on SADI-S identified from PubMed, ClinicalTrials.gov, and Google Scholar, from 2010 to 2023. Recent studies have consistently shown that SADI-S leads to significant weight reduction, with an average excess weight loss of 60 –80% within one year. Moreover, diabetes remission rates range from 60 to 90%, accompanied by improvements in metabolic parameters, such as fasting blood glucose, HbA1c levels, and insulin resistance. Positive changes in lipid profiles, including reductions in total cholesterol and triglyceride le vels, have also been observed. Although adverse events such as anastomotic leaks, wound infections, and nutritional deficiencies occur, they are generally manageable.SummaryThe SADI-S procedure demonstrates promising outcomes as a surgical treatment option for patients with diabetes and severe obesity. It not only results in significant weight loss but also leads to high rates of diabetes remission and improvements in metabolic parameters. Despite potential adverse events, the benefits of SADI-S outweigh the risks, making it a viable option for eligible patients.
Source: Current Surgery Reports - Category: Surgery Source Type: research