Gli1-mediated tumor cell-derived bFGF promotes tumor angiogenesis and pericyte coverage in non-small cell lung cancer

CONCLUSION: The Gli1-bFGF axis is crucial for the crosstalk between lung cancer cells and vascular cells. Targeting Gli1 is a potential therapeutic approach for NSCLC angiogenesis.PMID:38493151 | PMC:PMC10944600 | DOI:10.1186/s13046-024-03003-0

Source: Clinical Lung Cancer - March 17, 2024 Category: Cancer & Oncology Authors: Xueping Lei Zhan Li Manting Huang Lijuan Huang Yong Huang Sha Lv Weisong Zhang Zhuowen Chen Yuanyu Ke Songpei Li Jingfei Chen Xiangyu Yang Qiudi Deng Junshan Liu Xiyong Yu Source Type: research