Selective activation of IFN γ-ipilimumab enhances the therapeutic effect and safety of ipilimumab

CONCLUSION: IFNγ-ipilimumab improved the effectiveness of ipilimumab while reducing its side effects. It is likely that future immunotherapies would rely on such antibodies to activate local cancer cells or immune cells, thereby increasing the therapeutic effectiveness of cancer treatments and ensuring their safety.PMID:38493818 | DOI:10.1016/j.ijbiomac.2024.130945

Source: International Journal of Biological Macromolecules - March 17, 2024 Category: Biochemistry Authors: Yi-Jung Huang Kai-Wen Ho Tian-Lu Cheng Yen-Tseng Wang Shi-Wei Chao Bo-Cheng Huang Yu-Shu Chao Chia-Yu Lin Yun-Han Hsu Fang-Ming Chen Chih-Hung Chuang Source Type: research