Right ventricular pressure-strain relationship-derived myocardial work reflects contractility: validation with invasive pressure-volume analysis
Three-dimensional (3D) echocardiography-derived right ventricular (RV) ejection fraction (EF) and global longitudinal strain (GLS) are valuable RV functional markers; nevertheless, they are substantially load-dependent. Global myocardial work index (GMWI) is a novel parameter calculated by the area of the RV pressure-strain loop. By adjusting myocardial deformation to instantaneous pressure, it may reflect contractility.To test this hypothesis, we enrolled 60 patients who underwent RV pressure-conductance catheterization to determine load-independent markers of RV contractility and ventriculo-arterial coupling.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: B álint Károly Lakatos, Zvonimir Rako, Ádám Szijártó, Bruno R. Brito da Rocha, Manuel J. Richter, Alexandra Fábián, Henning Gall, Hossein A. Ghofrani, Nils Kremer, Werner Seeger, Daniel Zedler, Selin Yildiz, Athiththan Yogeswaran, Béla Merkely, K Tags: Brief Communication Source Type: research
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