Endocrine and non-endocrine causes of fatigue in adults with Neurofibromatosis type 1

ConclusionsEndocrine and non-endocrine disorders were equally present in our cohort of NF1 adults with and without fatigue. This suggests that the high prevalence of fatigue in NF1 adults is not explained by these somatic disorders. An alternative explanation for fatigue might be deficits in cognitive functioning and other neuropsychological processes in NF1. Based on our results and review of the literature, we provide a clinical algorithm for the approach to fatigue in NF1 adults, including somatic and psychological assessment.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research