Impact of combined alpha-lipoic acid and mitoquinone supplementation on myocardial infarction in aged rats: Heart performance and molecular mechanisms

CONCLUSION: The study revealed that combined intervention synergistically mitigated cardiac dysfunction by suppressing inflammatory and apoptotic pathways in aged rats with MI. Further research is needed to validate the potential of ALA and Mito Q as therapeutic options for elderly people at risk of heart attacks.PMID:38484905 | DOI:10.1016/j.exger.2024.112402

Source: Experimental Gerontology - March 14, 2024 Category: Geriatrics Authors: Samira Nemati Zohreh Zavvari-Oskuye Soleyman Bafadam Behnaz Mokhtari Reza Badalzadeh Abedin Vakili Source Type: research