Mechanism of moxibustion in treating chronic inflammatory visceral pain: regulation of the p38 MAPK/ELK1 signaling pathway in the spinal cord

ConclusionHPM exerted analgesic effects via downregulating the mRNA and phosphorylated protein expression of ASK1, MKK3, p38 MAPK, and ELK1 in the spinal cord of CIVP rats. The inhibition of spinal p38 MAPK/ELK1 signaling pathway activation may be one of the mechanisms by which HPM relieves pain in CIVP.
Source: Journal of Acupuncture and Tuina Science - Category: Complementary Medicine Source Type: research