Targeting the intracellular neurexin interactome by in vivo proximity ligation

Trends Neurosci. 2024 Mar 6:S0166-2236(24)00023-7. doi: 10.1016/j.tins.2024.02.007. Online ahead of print.ABSTRACTIn a recent study, Profes, Tiroumalechett, and colleagues used the in vivo proximity ligation technique TurboID to scrupulously characterize the interactome of the intracellular domain (ICD) of neurexin, revealing that this domain may be involved in presynaptic actin assembly by interacting with actin-associated proteins.PMID:38453567 | DOI:10.1016/j.tins.2024.02.007

Source: Trends in Neurosciences - March 7, 2024 Category: Neuroscience Authors: Ming-Han Wang Yue Hao Xia-Jing Tong Source Type: research