The T1-weighted/T2-weighted ratio as a biomarker of anti-NMDA receptor encephalitis

Conclusions The T1w/T2w ratio detects microstructural changes in grey and white matter of patients with NMDAR encephalitis that correlate with cognitive performance. Computable from conventional clinical MRI sequences, this measure shows promise in bridging the clinico-radiological dissociation in NMDAR encephalitis and could serve as an imaging outcome measure in clinical trials.

http://jnnp.bmj.com/cgi/content/short/95/4/366?rss=1

Source: Journal of Neurology, Neurosurgery and Psychiatry - March 13, 2024 Category: Neurosurgery Authors: Hartung, T. J., Cooper, G., Jünger, V., Komnenic, D., Ryan, L., Heine, J., Chien, C., Paul, F., Prüss, H., Finke, C. Tags: Open access Neuro-inflammation Source Type: research