High-efficiency EGFR genotyping using cell-free DNA in bronchial washing fluid

CONCLUSIONS: Using supernatant of bronchial washing fluid samples, the detection rate of EGFR mutation was high, and EGFR mutations were detectable even when no tumor cells had been detectable by biopsy or cytology. Supernatant of bronchial washing fluid might be an effective sample source for EGFR mutation testing.PMID:38476004 | DOI:10.1093/jjco/hyae021

Source: Clinical Lung Cancer - March 13, 2024 Category: Cancer & Oncology Authors: Yoshihiko Murata Yumi Nakajima Yukio Sato Nobuyuki Hizawa Daichi Yamakawa Daisuke Matsubara Masayuki Noguchi Yuko Minami Source Type: research