Validating a Four-gene Set for H-ARS Severity Prediction in Peripheral Blood Samples of Irradiated Rhesus Macaques

In conclusion, the diagnostic significance for radiation-induced H-ARS severity prediction of FDXR, DDB2, and POU2AF1 was confirmed in this Rhesus macaques model. However, DDB2 showed higher GE values than FDXR. As shown in previous studies, the diagnostic significance of WNT3 could not be reproduced in Rhesus macaques; this could be due to the choice of animal model and methodological challenges.PMID:38471521 | DOI:10.1667/RADE-23-00162.1

Source: Radiation Research - March 12, 2024 Category: Physics Authors: D Schwanke S Sch üle S Stewart O O Fatanmi S Y Wise C Hackenbroch T Wiegel V K Singh M Port M Abend P Ostheim Source Type: research