Remedial Dosing Recommendations for Sirolimus Delayed or Missed Dosages Caused by Poor Medication Compliance in Pediatric Tuberous Sclerosis Complex Patients

CONCLUSION: It was the first time to recommend remedial dosages for delayed or missed sirolimus therapy caused by poor medication compliance in pediatric TSC patients based on Monte Carlo simulation. Meanwhile, the present study provided a potential solution for delayed or missed dosages in clinical practice.PMID:38454763 | DOI:10.2174/0113816128299479240213151714

Source: Current Pharmaceutical Design - March 8, 2024 Category: Drugs & Pharmacology Authors: Yang Yang Lei Jiang Hai-Rong Zhu Wen-Xin Sun Jing-Yu Mao Jing-Wen Miao Yi-Chen Wang Su-Mei He Dong-Dong Wang Xiao Chen Source Type: research