Adipokine secretion and lipolysis following gender-affirming treatment in transgender individuals

ConclusionIn TW, gonadal hormone suppression results in transient changes in cytokines and in TM there are some changes in NA-stimulated lipolysis following testosterone treatment. However, despite the known metabolic effects of sex hormones, the overall effects of GAHT on adipose tissue function are small and likely have limited clinical relevance, but larger studies with longer follow-up are needed to confirm these findings.Trial registrationClinicalTrials.gov Identifier: NCT02518009, Retrospectively registered 7 August 2015.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research