Long-term antigen-specific immune response by an oncolytic adenovirus encoding SP-SA-E7-4-1BBL in HPV-16 cancer model

CONCLUSIONS: The OAd SP-SA-E7-4-1BBL vaccine confers a prophylactic, safe, long-lasting, and antigen-dependent antitumor effect mediated by a Th1 antitumor immune response.PMID:38460043 | DOI:10.1007/s11033-024-09303-0

Source: Molecular Biology Reports - March 9, 2024 Category: Molecular Biology Authors: Alejandra G Martinez-Perez Rodolfo Garza-Morales Maria de J Loera-Arias Sheila A Villa-Cedillo Aracely Garcia-Garcia Humberto Rodriguez-Rocha Orlando E Flores-Maldonado Jesus Valdes Jose J Perez-Trujillo Odila Saucedo-Cardenas Source Type: research