Spontaneous blink-related beta power increase and theta phase reset in subthalamic nucleus of Parkinson patients during walking

CONCLUSION: Our findings show that spontaneous blinking is related to striatal dopamine and has a frequency specific deployment in the STN. This correlation depends on the current movement state such as walking.SIGNIFICANCE: This work indicates that subcortical activity following a motor event as well as the relationship between dopamine and motor events can be dependent on the motor state. Accordingly, disease related changes in brain activity should be assessed during natural movement.PMID:38432185 | DOI:10.1016/j.clinph.2024.02.019
Source: Clinical Neurophysiology - Category: Neurology Authors: Source Type: research