Stereotactic body radiotherapy (SIB-VMAT technique) to dominant intraprostatic lesion (DIL) for localized prostate cancer: a  dose-escalation trial (DESTROY-4).

ConclusionThis trial confirms the feasibility and safety of a  total SIB-VMAT dose of 35 Gy on the whole gland and 50 Gy on DIL in 5 fractions daily administered in a well-selected low- and intermediate-risk prostate carcinoma population. A phase II study is ongoing to confirm the tolerability of the schedule and assess the efficacy.
Source: Strahlentherapie und Onkologie - Category: Cancer & Oncology Source Type: research