Nanoscale imaging of pT217-tau in aged rhesus macaque entorhinal and dorsolateral prefrontal cortex: Evidence of interneuronal trafficking and early-stage neurodegeneration

DISCUSSION: These data help to explain why pT217-tau predicts degeneration in AD and how it gains access to CSF and plasma to serve as a fluid biomarker.PMID:38445818 | DOI:10.1002/alz.13737

Source: The Journal of Alzheimers Association - March 6, 2024 Category: Psychiatry Authors: Dibyadeep Datta Isabella Perone Denethi Wijegunawardana Feng Liang Yury M Morozov Jon Arellano Alvaro Duque Zhongcong Xie Christopher H van Dyck Mary Kate P Joyce Amy F T Arnsten Source Type: research