Implications of IFN γ SNP rs2069705 in Primary Sjögren's Syndrome: Transcriptional Activation and B Cell Infiltration

CONCLUSION: SNP rs2069705 in the IFNγ gene emerges as a pivotal element in pSS susceptibility, primarily by augmenting IFNγ transcription, activating the JAK/STAT1 pathway, and leading to B lymphocyte infiltration in the exocrine glands.PMID:38406824 | DOI:10.1152/ajpcell.00661.2023
Source: Am J Physiol Cell Ph... - Category: Cytology Authors: Source Type: research